12 results found for: “hfref”.

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Heart failure

fraction (HFrEF): Synonyms no longer recommended are "heart failure due to left ventricular systolic dysfunction" and "systolic heart failure". HFrEF is associated...

Last Update: 2024-03-15T10:02:00Z Word Count : 15476 Synonim Heart failure

Heart failure with preserved ejection fraction

ejection fraction, called heart failure with reduced ejection fraction (HFrEF). Risk factors for HFpEF include hypertension, hyperlipidemia, diabetes...

Last Update: 2024-02-13T18:54:18Z Word Count : 7078 Synonim Heart failure with preserved ejection fraction

XXB 750

Tolerability Study of XXB750 in Heart Failure Participants With Reduced or Mildly Reduced Ejection Fraction (HFrEF/HFmrEF)". Retrieved 23 November 2023....

Last Update: 2023-12-20T20:08:48Z Word Count : 87 Synonim XXB 750

Vericiguat

Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-001) (VICTORIA)" at ClinicalTrials.gov Portal:  Medicine...

Last Update: 2024-03-03T05:07:53Z Word Count : 928 Synonim Vericiguat

Ejection fraction

moderately reduced LVEF [in the range of 41–49%] (HFmrEF) reduced LVEF [≤40%] (HFrEF)] A chronically low ejection fraction less than 30% is an important threshold...

Last Update: 2023-11-07T07:41:25Z Word Count : 2209 Synonim Ejection fraction

Dapagliflozin

hospitalization, cardiovascular death, and all-cause mortality in patients with HFrEF (i.e., congestive heart failure) and diabetes. "Dapagliflozin (Farxiga)...

Last Update: 2024-03-02T23:26:32Z Word Count : 4777 Synonim Dapagliflozin

List of medical abbreviations: H

virus HF heart failure HFpEF heart failure with preserved ejection fraction HFrEF heart failure with reduced ejection fraction HFM hand, foot and mouth disease...

Last Update: 2023-11-17T15:12:08Z Word Count : 0 Synonim List of medical abbreviations: H

Cytokinetics

" Cardiovascular Business. 5 Dec 2015. [3] "Novel myosin activator for HFrEF nets FDA fast track designation". www.healio.com. Retrieved 2020-08-27....

Last Update: 2024-03-20T16:26:43Z Word Count : 608 Synonim Cytokinetics

January–March 2023 in science

MPC[clarification needed] stem cell therapy against cardiac events in people with HFrEF heart failure (27 Feb). Progress in screening or diagnosis: a news-reported...

Last Update: 2024-03-25T05:43:00Z Word Count : 28831 Synonim January–March 2023 in science

Commonly prescribed drugs

(asthma) Severe Peripheral Arterial Disease (critical limb ischemia) Unstable HFrEF Diabetes with frequent episodes of hypoglycemia Calcium Channel Blockers...

Last Update: 2023-12-12T08:25:45Z Word Count : 3277 Synonim Commonly prescribed drugs

Diabetic cardiomyopathy

phenotypes (HFREF). HFPEF results predominantly from hyperinsulinemia, hyperglycemia, lipotoxicity, AGEs and microvascular rarefication. HFREF is associated...

Last Update: 2024-03-28T02:52:18Z Word Count : 2361 Synonim Diabetic cardiomyopathy

Wearable cardioverter defibrillator

diagnosed Ischemic Heart Failure Patient with Reduced Ejection Fraction (HFrEF) For at least 90 days of optimal medical therapy Patients with ventricular...

Last Update: 2023-12-03T11:20:01Z Word Count : 5559 Synonim Wearable cardioverter defibrillator

Main result

Heart failure

Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome, a group of signs and symptoms, caused by an impairment of the heart's blood pumping function. Symptoms typically include shortness of breath, excessive fatigue, and leg swelling. The shortness of breath may occur with exertion or while lying down, and may wake people up during the night. The severity of the heart failure is mainly decided based on ejection fraction and also measured by the severity of symptoms. Other conditions that may have symptoms similar to heart failure include obesity, kidney failure, liver disease, anemia, and thyroid disease.Common causes of heart failure include coronary artery disease, heart attack, high blood pressure, atrial fibrillation, valvular heart disease, excessive alcohol consumption, infection, and cardiomyopathy. These cause heart failure by altering the structure or the function of the heart or in some cases both. There are different types of heart failure: right-sided heart failure, which affects the right heart, left-sided heart failure, which affects the left heart, and biventricular heart failure, which affects both sides of the heart. Left-sided heart failure may be present with a reduced ejection fraction or with a preserved ejection fraction. Heart failure is not the same as cardiac arrest, in which blood flow stops completely due to the failure of the heart to pump.Diagnosis is based on symptoms, physical findings, and echocardiography. Blood tests, and a chest x-ray may be useful to determine the underlying cause. Treatment depends on severity and case. For people with chronic, stable, mild heart failure, treatment usually consists of lifestyle changes, such as not smoking, physical exercise, and dietary changes, as well as medications. In heart failure due to left ventricular dysfunction, angiotensin-converting-enzyme inhibitors, angiotensin receptor blockers, or angiotensin receptor-neprilysin inhibitors, along with beta blockers, mineralocorticoid receptor antagonists and SGLT2 inhibitors are recommended. Diuretics may also be prescribed to prevent fluid retention and the resulting shortness of breath. Depending on the case, an implanted device such as a pacemaker or implantable cardiac defibrillator may sometimes be recommended. In some moderate or more severe cases, cardiac resynchronization therapy (CRT) or cardiac contractility modulation may be beneficial. In severe disease that persists despite all other measures, a cardiac assist device ventricular assist device, or, occasionally, heart transplantation may be recommended.Heart failure is a common, costly, and potentially fatal condition, and is the leading cause of hospitalization and readmission in older adults. Heart failure often leads to more drastic health impairments than failure of other, similarly complex organs such as the kidneys or liver. In 2015, it affected about 40 million people worldwide. Overall, heart failure affects about 2% of adults, and more than 10% of those over the age of 70. Rates are predicted to increase. The risk of death in the first year after diagnosis is about 35%, while the risk of death in the second year is less than 10% in those still alive. The risk of death is comparable to that of some cancers. In the United Kingdom, the disease is the reason for 5% of emergency hospital admissions. Heart failure has been known since ancient times; it is mentioned in the Ebers Papyrus around 1550 BCE.


hfref